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But due to the following factors, its levels deplete in the body: Stress Medication and Drugs Pollution Poor Diet Toxin buildup leading to increased oxidative stress Aging Keeping in mind the lifestyle of metrocities that includes poor diet, sleep and even habits like smoking and occasional alcohol consumption, Glutathione levels suffer in the process of upkeep and neutralising of free radicals

Nat Immunol (2021) 22(9):112739

Another interesting finding is the abnormally high post-prandial oxidative stress for individuals in MUO group after the HP meal challenges (Fig

doi: 10.1177/08853282211058099 13 BaltimoreR

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Interestingly, polarization of M2 macrophages is also associated with HO-1 expression in diabetes [35, 36]