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Recent studies show that individuals with reduced or mutated VDR expression exhibit elevated malondialdehyde (MDA) levels and decreased GSH/GSSG ratios in the skin, indicative of impaired antioxidant capacity and reaffirming the centrality of VDR signaling in maintaining redox homeostasis

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335,339 These deficits may be attributable to increased signalling by IL-1 secreted from microglia

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in: PubMed | Google Scholar 1 Department of Endocrinology, Diabetology and Metabolism, University Hospital Basel, Basel, Switzerland

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