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While the designed complex successfully blocks FcR interactions, it retains binding to FcRn as measured by SPR, comparable to the parental antibody (Fig

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Conversion of the peptide to the C -terminal thioester allowed a second NCL cycle with Cys, which then underwent radical-mediated desulfurization following Danishefsky's method (Wan and Danishefsky, 2007)

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[1] Skin lightening or bleaching refers to the cosmetic practice of applying depigmenting agents not as treatment for hyperpigmentation but with the deliberate aim of achieving a lighter skin colour

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