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10.1074/jbc.M115.678235 101 ThorupA

Because your body is constantly producing glutathioneand less is required while you sleepyour GSH stores increase in preparation for the next day, Staheli says

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Elevate homocysteine levels, impairing normal blood vessel function, promoting oxidative stress, and increasing risk of atherosclerosis, cardiovascular disease, insulin resistance, and Type 2 diabetes

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For example, if you are adding mushrooms rich in glutathione, like Reishi or Chaga, start with small amounts mixed into your dog's regular meals (or a high-quality supplement) and observe your dog to see how their body reacts