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Our friends at TrustPointe have provided the following detailed explanation to help interpret the results of the endotoxin testing

IS HORMONE THERAPY RIGHT FOR YOUR PATIENTS

Adiponectin provides protective metabolic signaling and declines with adiposity, lifting a brake on inflammation and insulin sensitivity that then affects estrogen and progesterone homeostasis

The rubber stopper, however, can be a weak point

However such associations are unlikely to be causal - it is much more likely that the high vitamin B12 is just a marker that associates with such serious disease