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But the bigger picture, the former FDA leaders argued, is that the new proposals would reject long-standing science about how to evaluate vaccines being updated to better match virus strains, slow innovation to replace older vaccines with newer, potentially better ones, and make the process less transparent to the public

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Based on leaky phenotypes of secretin gate mutant strains, this structure appears to restrict the size of the secretin pore to that of typical porins, preserving the outer membranes barrier function 22,23,24,25

The uptake of soluble and particulate antigens by epithelial cells in the mouse small intestine