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Pharmaceutics 13:38
Transdermal and microneedle approaches are primarily studied in laboratory contexts to assess pharmacokinetics and tolerability rather than to provide guidance for human therapeutic use
Citations Wilding JPH, et al
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Vitamin C (ascorbic acid or ascorbate) can be converted to oxalates but the biochemical conversion system is saturated at low levels of vitamin C so that no additional oxalate is formed until very large doses (greater than 4 g per day) are consumed