what is a known effect of glp-1 for Weight Loss and Diabetes Long-Term Effects Of GLP-1 Medications:

The exenatide group in this study, however, showed a significant increase in the mean cardiac output by 1.2 L/min, a reduced total peripheral resistance by the mean of 120 dyns/cm 5 , and a significantly reduced urinary sodium: creatinine ratio without a significant change in the BP [39]

Wegovy, on the other hand, is approved by the FDA for weight loss

Its defined amino acid sequence makes it a common reference compound in peptide biology studies

Most protocols begin at 0.5 mg to 2 mg administered subcutaneously once per week

Each small tick mark = 1 unit (0.01 mL)

This reduces binding affinity to GLP-1 receptors, meaning each molecule is less effective at triggering the biological response you need