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Diallyl trisulfide-induced apoptosis of bladder cancer cells is caspase-dependent and regulated by PI3K/Akt and JNK pathways

24 Therefore, considering that GLP-1R is widely distributed in the body, that COPD and diabetes interact with each other and share common pathogenic mechanisms, and that GLP-1 and its receptor agonists have been widely used in diabetic patients and have demonstrated hypoglycemic, pro-inflammatory and anti-inflammatory factors, oxidative stress, neurogenesis and vascular protection, 33 then GLP-1 and its receptor agonists also have a role to play in COPD patients

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The FDA notes that tirzepatide may cause side effects such as nausea, diarrhea, vomiting, constipation, abdominal discomfort, injection site reactions, fatigue and reflux

High serum pentosidine concentrations are associated with increased arterial stiffness and thickness in patients with type 2 diabetes