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They may get little to no B12 from their food, because vitamin B12 only occurs naturally in animal sources

Myelin acts like insulation around nerve fibers

As a lipidated amylin analogue, maintaining structural fidelity is particularly important because receptor binding and signaling activity depend on the peptide's engineered sequence modifications and lipidation profile [1]

I.PletinkovaO.et al (2011)

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However, the addition of diuretic therapy has been shown to sensitize African American patients to these agents to obtain similar responses as in nonAfrican American patients