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Neck lumps, difficulty swallowing, hoarseness, or shortness of breath should be reported to a provider immediately

The trial randomised adults with obesity who have achieved 5% WL by the end of the 12-week lead-in period (mean WL at the lead-in period was 6.9%) to placebo or tirzepatide

To reduce bruising, avoid areas with visible veins, do not rub the site after injection, and make sure you are rotating sites weekly

Needle: 30G or 31G, 6 mm fixed needle insulin syringe

Many attempts have been made to make weight loss prescriptions widely available since at least the 1930s

The number of events was 668 in the placebo group compared with 579 in the oral semaglutide group, supporting a consistent CV benefit (60)