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Curr Diab Rep 19 , 138 (2019)

doi:10.1016/S0140-6736(13)62674-4

B12 functions as a cofactor in cellular metabolism but does not directly cause fat reduction or appetite suppression

Common Vitamin B12 deficiency symptoms Numbness, or tingling in the hands, legs, or feet, difficulty walking, anemia, a swollen, inflamed tongue, difficulty thinking and reasoning, or memory loss, weakness, and fatigue

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Its research profile makes it especially relevant for studies focused on fat-cell pathway models, metabolic turnover, energy-balance signaling, methylation-adjacent biology, and body-composition pathway research