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Research shows that MOTS-c improves insulin sensitivity, reduces lipid accumulation, and enhances glucose utilization

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HEALTHY AGING Reduce cell damage caused by fatty liver disease Antioxidant deficiencyincluding a lack of glutathionecan exacerbate cell death in the liver and lead to fatty liver disease

Notably, in line with the previous findings that intestinal FXR was not required for maintaining the normal glucose homeostasis 32 , the glucose metabolism was normal in IFXRKO mice in euthyroid state, suggesting that compensatory mechanisms may exist (Supplementary Fig

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