Early data suggest that weight loss drugs like semaglutide decrease the risk of colorectal cancer
GI side effects, the most reported, include nausea, vomiting, constipation, and diarrhea
Today I took my second injection and I am having orange urine since then and extreme pain in one leg
The mechanism behind this improved tolerability involves receptor interactions in the gut and brain
In cardiovascular outcome trials (CVOTs) such as Empagliflozin Cardiovascular Outcome Event Trial in Type 2 diabetes Mellitus Patients (EMPA-REG OUTCOME), CANagliflozin cardioVascular Assessment Study (CANVAS) and The Dapagliflozin Effect on Cardiovascular EventsThrombolysis in Myocardial Infarction 58 (DECLARE-TIMI 58) [6], they reduced the onset and progression of DKD, which was confirmed in the dedicated kidney trial The Canagliflozin and Renal Endpoints in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE), which showed a canagliflozin-induced risk reduction for ESKD in people with DKD by 32% [7]
Who should get an annual flu shot