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J Clin Endocrinol Metab (2011) 96(6):185963

A separate patient experienced sudden chills, fever and shaking and was admitted for assessment of a possible bloodstream infection

This rate sounds high until you understand the context

Several factors, including age and body fat, can affect BAC levels.

Risks of Improper Handling Loss of activity Aggregation and insolubility Bacterial contamination Chemical degradation Inconsistent results Pre-Reconstitution Preparation Sterility: Always work in a clean environment