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For cell treatment by APAP precursors, HepaRG cells and primary human hepatocytes were first incubated with 50 g/ml of APAP or APAP-cys in the maintenance medium described above, during 0.5 h, 2 h, 6 h, 24 h, or 48 h, to optimize the incubation time required to detect APAP metabolites

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This heat sensitive product can be exposed to high temperatures for short periods of time (5-7 days) with no damage to the product

Mol Biotechnol (2012) 51(2):18399

Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells