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Archived from the original on 20 February 2020

Adems de la inspeccin visual, est atento a seales clnicas de medicamento ineficaz : Si nota un control glucmico deteriorado sin explicacin (niveles de glucosa en sangre consistentemente elevados), aumento del apetito o prdida del efecto teraputico esperado, esto puede indicar que el medicamento ha perdido potencia debido al almacenamiento inadecuado

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Together these data demonstrate that in DIO mice the GLP-1 peptide component of MEDI4166, despite being 52- and 37-fold less potent than Ab#2.1_EX4 at mouse GLP-1R in CHO transfected cells and MIN6 -cells respectively (Supplementary Table 9), resulted in more durable glucose control than the non-optimised fusion

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