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The cohort comprised patients over 20 years old who were newly treated with glucose-lowering drugs between 1 January 2013 and 31 December 2021, and followed until 30 September 2022
Although controversial, albumin may transcytose through the BBB via caveolae-mediated vesicular trafficking, which although present, is greatly restricted in the BBB [18]
Alcohol depletes glutathione: Chronic alcohol consumption severely reduces hepatic glutathione through increased oxidative stress during ethanol metabolism [6][35]
Internal Medicine 177 (9), ITC129ITC144
Coagulopathy can be quickly treated with a single dose of 10 mg (to be administered parenterally in patients with impaired absorption), which can be repeated after 4872 h (92)
This disruption can lead to the accumulation of toxic proteins and cellular components, contributing to cell death and exacerbating brain damage [59,60]
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