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Abbreviations ADA: American Diabetes Association ADVANCE: Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation AHA: American Heart Association ASCVD: Atherosclerotic Cardiovascular Disease A1C/HbA1c: Hemoglobin A1c (Glycated Hemoglobin) ARB: Angiotensin II Receptor Blocker ACE-I: Angiotensin-Converting Enzyme Inhibitor BNP: B-type Natriuretic Peptide CBC: Complete Blood Count CKD: Chronic Kidney Disease CVD: Cardiovascular Disease DKA: Diabetic Ketoacidosis DKD: Diabetic Kidney Disease DM: Diabetes Mellitus DPP-4: Dipeptidyl Peptidase-4 eGFR: Estimated Glomerular Filtration Rate ESC: European Society of Cardiology ESRD: End-Stage Renal Disease FPG: Fasting Plasma Glucose GB: Gallbladder GLP-1 RAs: Glucagon-Like Peptide-1 Receptor Agonists GIT: Gastrointestinal Tract HCP: Healthcare Provider HF: Heart Failure HFmrEF: Heart Failure with Mildly Reduced Ejection Fraction HFpEF: Heart Failure with Preserved Ejection Fraction HFrEF: Heart Failure with Reduced Ejection Fraction IDF: International Diabetes Federation IU: International Unit LDL-C: Low-Density Lipoprotein Cholesterol MAFLD: Metabolic Dysfunction-Associated Fatty Liver Disease NAFLD: Non-Alcoholic Fatty Liver Disease NPH: Neutral Protamine Hagedorn OHA: Oral Hypoglycemic Agent PCSK9: Proprotein Convertase Subtilisin/Kexin Type 9 PPG: Postprandial Glucose RAAS: Renin-Angiotensin-Aldosterone System SCORE2: Systematic Coronary Risk Estimation 2 SMPG: Self-Monitored Plasma Glucose SGLT2: Sodium-Glucose Cotransporter-2 SU: Sulfonylurea T1DM: Type 1 Diabetes Mellitus T2DM: Type 2 Diabetes Mellitus TDD: Total Daily Dose TOD: Target-Organ Damage TZDs: Thiazolidinediones UACR: Urinary Albumin-to-Creatinine Ratio References Kharroubi AT, Darwish HM

Eating frequent small meals may minimize the side effects

Previous metabolomic studies of BPD, with similar analytical techniques to our study, have focused on preterm-born infants in the neonatal period

Synthesis of Dimeric phenol derivatives and determination of in vitro antioxidant and radical scavenging activities

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This connection influences hunger, satiety, and even emotional eating