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Astrocyte senescence may drive alterations in GFAP, CDKN2A p14ARF, and TAU3 transcript expression and contribute to cognitive decline

Endothelial SIRT6 is vital to prevent hypertension and associated cardiorenal injury through targeting Nkx3.2-GATA5 signaling

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These results are often better than what people see with diet and exercise alone or some other medications

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Lahring J, Leifheit-Nestler M, Ewert A, Herzig N, Koppl C, Pott V, Oh J, Buscher A, Thumfart J, Weber LT, Arbeiter K, Acham-Roschitz B, Tonshoff B, Zivicnjak M, Hohenfellner K, Haffner D (2024) Cystinosis-associated metabolic bone disease across ages and CKD stages 15D/T