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Neuroscience (2011) 185:97105.10.1016/j.neuroscience.2011.04.041 80 NguyenDAlaviMVKimK-YKangTScottRTNohYHet alA new vicious cycle involving glutamate excitotoxicity, oxidative stress and mitochondrial dynamics

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The peptide functions as a precision senolytic agent by competing with endogenous FOXO4 for p53 binding, releasing the tumor suppressor protein to trigger apoptosis specifically in cells that have accumulated the senescence-associated secretory phenotype (SASP) markers

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