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Together, these steps outline a conceptual plant screening-animal validation pipeline in which genetically tractable Arabidopsis systems enable the discovery of GLR-related redox regulators, while mammalian neuronal models provide the physiological context required for translational interpretation

This was evidenced by a decreased requirement for intensification of treatment associated with better preservation of glycemic control, as well as better sustained -cell function as reflected in the fasting HOMA-2 during the 2-year follow-up period

CLML 13(S2):S376-77, 2013

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