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The reasons for this bad prognosis were positive lymph node metastasis, T34 stages, hepatic invasion, and R1 resection [206]

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Individuals with certain genetic predispositionssuch as variants in methionine synthase (MTHFR) and cobalamin metabolism pathwaysmay respond more distinctly to B vitamin protocols

Long-term data on the sustainability of weight loss and the safety of retatrutide are also lacking, emphasizing the need for further research