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To determine the tolerable upper intake level (UL), the FNB selected adverse reproductive effects in rats as the most sensitive index of toxicity and applied a large uncertainty factor because animal data were used (2)

Carnitine to TMAO conversion varies widely between individuals with reports that, for some, as much as ~50% of ingested carnitine is eventually excreted in the urine as TMAO (Rebouche 1991)

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Effects of cranial radiation on hypothalamic-adenohypophyseal function: abnormal growth hormone secretory dynamics

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