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Animal models provide proof of concept but do not translate directly to human androgenetic alopecia, which involves hormonal mechanisms absent in mouse models

We found that reduced UA and agricultural work, proxy for increased exposure to pesticides, were both associated with PD in the same cohort 13 , although the study was not designed to identify interaction effects

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That asymmetry is the central reason clinicians treat this as a case-by-case judgment rather than a standard protocol