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The overexpression of critical autophagic genes exhausts the levels of the mutant p53 protein, and treating cells with autophagy inhibitors increases the stability of mutant p53

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Pharmaceutical companies increasingly apply AI to: predict protein structures (e.g

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[DOI] [PubMed] [Google Scholar] 32.Effects of low-dose, controlled-release, phentermine plus topiramate combination on weight and associated comorbidities in overweight and obese adults (conquer): a randomised, placebo-controlled, phase 3 trial

The highest comorbidity (Presence of two or more health conditions at once in the same person) associated with obesity is T2DM