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Pyridoxine (B) in high doses is known to interact with certain drugs: it can reduce the therapeutic efficacy of levodopa by increasing peripheral conversion of levodopa to dopamine (vitamin B speeds up decarboxylation)

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While LR3 will distribute systemically regardless, IM injection into a muscle about to be trained might provide slightly enhanced local effects

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Hydroxocobalamin (Vitamin B) Injection Hydroxocobalamin (Vitamin B) is a sterile intramuscular injection delivering 1,000 g/mL of hydroxocobalamin acetate

The choice is dictated by client preference, the reason for the deficiency, and the tolerance to a given supplement