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By 2050, the burden of stroke in individuals (aged 65 years) will increase significantly: 104.7% in incidence, 218.5% in prevalence, 100.0% in mortality, and 58.9% in DALYs (54)

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Unlike small-molecule drugs that may remain stable at room temperature, peptide medications are sensitive to environmental factors including temperature fluctuations, light exposure, and physical agitation

looking at mortality only, the rates were 7% with dapagliflozin and 9% with placebo [106]

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