As with any other supplement, there is a possibility of an allergic reaction or interactions with other drugs you may be taking
That's a fancy way of saying it's three amino acids bound to a copper ion
GRAS simply means the FDA agrees that the substance, at intended use levels as a food additive or supplement, is safe based on common use history or expert opinion and does not pose acute toxicity concerns
Additionally, B12 can help boost energy levels, improve mood, and enhance cognitive function, all of which are important for maintaining an active and fulfilling lifestyle
In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years
Many unhealthy people with B12 deficiency, especially pernicious anemia patients, have trouble clearing our the cyanide
