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For instance, intact cells and cell-free extracts of Bifidobacterium animalis 01 can scavenge hydroxyl radicals and superoxide anion in vitro , whereas in vivo , they increase the antioxidative enzyme activity (225, 226)

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In addition, they found that let-7 bound directly 3UTR of IGF-1R as well as IRS-2 and insulin receptor (INSR) suggesting that let-7 may function as a regulator of glucose metabolism by targeting multiple components of growth/metabolic signaling pathway genes