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DPP-4 inhibitors in the management of type 2 diabetes: a critical review of head-to-head trials

In addition, there are a few conserved residues (e.g., Asp67, Trp72, Pro86, Gly108, and Trp110) that form specific interactions within the extracellular domain (see Figure 4 insets)

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It raises blood sugar, stimulates appetite, and reduces impulse control, often leading to overeating

(1) Kinetic method