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Metabolic Features of the Reproductive Phenotypes of Polycystic Ovary Syndrome

it was about getting the right support to make it work

Who Should Be Cautious Powerful metabolic medicines are not right for everyone

1,2 Initially developed as antidiabetic treatments, GLP-1 RAs and, more recently, dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists have demonstrated favourable metabolic outcomes with significant and sustainable weight loss in large randomised controlled trials (RCTs) and real-world studies

This structured screening ensures that only appropriate candidates receive therapy and that monitoring is in place where risks are identified

Here we highlight data informing the safety, efficacy, and potential utility of new and emerging glucagon-like peptide-1 medicines