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The most commonly reported issue is prolonged fullness or a sensation of excessive abdominal distension

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*Correspondence: Jun Xu, [email protected] This article was submitted to Endocrinology of Aging, a section of the journal Frontiers in Endocrinology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

GI side effects, if present, typically peak and then stabilize

A Phase 2, Randomized, Dose-Finding Study of the Novel Once-Weekly Human GLP-1 Analog, Semaglutide, Compared With Placebo and Open-Label Liraglutide in Patients With Type 2 Diabetes