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Single-cell RNA sequencing and machine learning provide candidate drugs against drug-tolerant persister cells in colorectal cancer

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The single human musculoskeletal paper that gets cited often is a small retrospective case series of intra-articular BPC-157 injections for multiple types of knee pain. It reported improvement in 11 of 12 patients, but the study has major limitations: no control group, no standardized objective outcome measures, no imaging confirmation of pathology, and unclear diagnostic specificity

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