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This is especially concerning for humans, as the molecular signalling in human disease is far more complex than in many animal models ( Figure 2 schematizes the two faces of lipid peroxidation

Finally, 10-formyl-THF can be converted back to THF via the actions of the cytoplasmic ALDH1L1 (aldehyde dehydrogenase 1 family member L1) encoded enzyme

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Samples were kept in the dark for an hour at room temperature (RT)

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