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These therapies display higher efficiency compared to classical senolytic drugs (BCL-2 or tyrosine kinase inhibitors) but for some of them, such as NA + /K + ATPase inhibitors, clinical development could be complex in the light of strong cardiotoxicity associated with this class of molecules

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5) Some medications like fluoxetine (an inhibitor of 5-HT capture) have both anti-inflammatory and anti-depressant effects (205, 300)

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