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These data collectively suggest that the observed increase in hepatic protein-SSG formation in HFD-fed animals can result from a combination of both increased S -glutathionylation processes and suppressed de-glutathionylation reactions

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This finding is consistent with studies that have demonstrated that some GLP-1 RAs, like Liraglutide, may be associated with modest reductions in fracture risks in patients with T2DM who have been prescribed a GLP-1 RA for at least one year (7, 8, 9)

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