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doi: 10.1016/j.gie.2024.04.2900

Available as: Last cited 8 Sept 2023 Ethics declarations Ethics approval and consent to participate Since it is a review article, they are not required

Read the latest GLP-1 Pipeline Update References DrugIQ Drug Search

Freezing can damage the peptide structure, making the medication unsafe or ineffective

Liu D, Pavlovic D, Chen MC, Flodstrm M, Sandler S, Eizirik DL (2000) Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-)

GLP-1 Secretion While GLP-1 secretion was originally described in response to glucose, it also occurs with ingestion of a mixed meal and the GLP-1 response is greater than to glucose alone indicating synergy in the stimulation by fat and protein along with glucose (1, 78, 132)