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In infiltrating macrophages within the disc microenvironment, GLP-1 potentiates STAT3 signaling to promote M2 polarization, fostering a pro-regenerative immune niche, while paradoxically attenuating pathological STAT3 phosphorylation in nucleus pulposus cells themselves to reduce cellular senescence

OConnor DB, Ferguson E, Green JA, OCarroll RE, OConnor RC

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Disulfide-bond-induced structural frustration and dynamic disorder in a peroxiredoxin from MAS NMR

In this model, Epitalon reduced the overall incidence of breast adenocarcinoma

Liothyronine is a synthetic form of the active thyroid hormone triiodothyronine (T3)