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References 1 Aguiar-OliveiraM

& Goebell, H

Mechanistically, GHRP-6 sustained cellular antioxidant defense, upregulated the prosurvival gene Bcl-2, and preserved cardiomyocyte mitochondrial integrity

Improved blood pressure control in this population could contribute meaningfully to symptom relief and better long-term outcomes.25 Improvement in glycemic control was evident among diabetic subgroups treated with GLP-1RAs, aligning with their established role in lowering blood glucose.26 However, the high heterogeneity observed among the studies indicates that the magnitude of this effect may be compromised by variability in the baseline characteristics such as HbA1c levels, duration of diabetes, different GLP-1RAs and their doses used

Thomas GB, Fairhall KM, Robinson IC

However, there is hope for cost reduction following the patent expiry of tirzepatide in 2026, which may allow for the introduction of more affordable generic versions