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The 0.25mg to 2.4mg titration schedule represents the optimal balance identified through these extensive research programs

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For the initial treatment of vitamin B12 deficiency, the usual dose is 100mcg SC/MC, given every day for 10-15 days, followed by maintenance treatment

MACS is associated with a high burden of cardiometabolic comorbidities, most commonly hypertension (80%) and diabetes (40%) [176]

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