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Intriguingly, 30 min before FeCl 3 injection, intraperitoneal injection of adenosine dichloride (Cl-Ado) or adenosine (Ado) inhibited or delayed the occurrence of FeCl 3 -induced epileptic discharge

The release of acidic metabolites such as lactate, generated by tumor cells via glycolysis, exacerbates local acidosis within the TME (90)

Patients should be encouraged to adopt practices that promote restful sleep and to seek support for any underlying issues that may contribute to insomnia

The method of embodiment 107, wherein the composition has an osmolarity from about 200 to about 400 mOsm/L

Results Patient characteristics A total of 817 patients were screened, and, of this group, 529 fulfilled eligibility criteria and were enrolled and randomized between 19 March 2021 and 9 March 2022 (Extended Data Fig

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