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MC4R activation promotes increased energy expenditure through stimulation of sympathetic nervous system activity, brown adipose tissue thermogenesis, and enhanced fatty acid oxidation
These results were groundbreaking at the time of publication and have since been reinforced by subsequent trials
This requires a level of health literacy and self-efficacy that not everyone possesses or is comfortable with
We look forward to working with policymakers, payers, clinicians and patient advocates to ensure that the promise of this announcement is realized in clinical practice including timely access, appropriate coverage, provider education, equitable care, and ongoing support for longterm outcomes. However Dr
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