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Taken together, these results suggest that endogenously produced persulfides protect against LPO and consequently prevent ferroptosis

This foundational discovery later recognized with the 2024 LaskerDeBakey Clinical Medical Research Award for Habener, Mojsov, and Lotte Bjerre Knudsen laid the foundation for an entirely new class of GLP-1 medications.[1] Gut releases natural GLP-1 that is destroyed in the bloodstream within about two minutes by the enzyme DPP-4 that is a widely distributed integral membrane protein that is expressed in the intestine, kidney, vascular endothelium, liver pancreas, glandular epithelial cells, and immune system cells.[17] Hence, DPP-4 inhibitors are a successful class of anti-hyperglycaemic agents used to treat type 2 diabetes (T2DM) via protecting GLP-1

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Hier ist Glutathion ein wichtiger Bindungspartner, mit dessen Hilfe die Stoffe umgewandelt werden knnen