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But 16.9% is still a strong result, and the blood sugar improvements were clinically significant

However, pain may not always be localized to this area

Overall, these findings are complementary to results in a companion article 57 , in which the body-weight-reducing and food-intake-reducing effects of GIPR antagonism are disrupted in mice with global loss of either Gipr or Glp1r but preserved in mice with loss of Gipr in either GABAergic or peripheral neurons

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