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Availability of data and materials Not applicable as we are submitting review article

If the bioavailability is low, most of that high dose is simply wasted

Preexisting cross-reactive T cells could contribute to rapid viral control due to the following characteristics: their adapted phenotype , as they are already differentiated to memory T cells poised to respond with rapid proliferation and immediate effector function

Its quite tolerable, and most report it as virtually painless

pH 5.5 - 8.5 Spring water

doi:10.1016/j.mehy.2012.07.034, PMID: 22951418 Marshall HE, Stamler JS (2001) Inhibition of NF-kappa B by S -nitrosylation