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GLP-1RAs also reduce intracranial pressure and alleviate headache symptoms associated with conditions like idiopathic intracranial hypertension, particularly in female patients [98101]

Landin K, Tengborn L, Smith U (1991) Treating insulin resistance in hypertension with metformin reduces both blood pressure and metabolic risk factors

The goal is to minimize that as much as possible

Important safety considerations include monitoring for diabetic retinopathy complications (especially with rapid HbA1c improvement), gallbladder disease, and dehydration risk

The anti-inflammatory properties of GLP-1 agonists additionally contribute to their cardiovascular benefits

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