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When used together, these overlapping side effects could be additive, potentially leading to greater patient discomfort or reduced treatment adherence

The orally disintegrating tablet formulation offers unique administration considerations that distinguish it from traditional oral medications or injectable GLP-1 receptor agonists

doi: 10.1126/science.1261833 129 SalmernA

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Injectable semaglutide achieves higher bioavailability and more consistent GLP-1 receptor activation, often resulting in greater weight loss and metabolic improvements