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A B12 shot is not a stimulant, so you should not expect a sudden caffeine-like jolt minutes after your appointment

Recommended Use: Vitamin B12 is recommended for those with fatigue, poor concentration, or low red blood cell levels

Furthermore, this review covers a detailed description of the nasal delivery devices

Dispose of the needle properly (in a sharps container, and not in your regular garbage return it to the docs office or a biohazard collection site!) After the B12 shot is injected into your upper arm, thigh, hip, or butt, you should experience benefits right away

Current published literature remains limited