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a continued downward slope suggests either the dose wasnt maximal, adherence held, or the biology stayed responsive
Interestingly, in people with type 2 diabetes mellitus, who often exhibit glomerular hyperfiltration, GLP-1 receptor agonists stabilize or modestly reduce eGFR, an effect reminiscent of the initial declines observed with RAAS and SGLT2 inhibitors [64]
Supplementary information Glossary B6.NZM2410.Sle1.Sle2.Sle3 triple-congenic mouse model A genetically engineered model on a C57BL/6 background combining three susceptibility loci from Sle, Sle2 and Sle3, leading to spontaneous lupus-like disease
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Badole SL, Bagul PP, Mahamuni SP, Khose RD, Joshi AC, Jangam GB, Ghule AE, Raut CG, Khedkar VM, Coutinho EC